Prostaglandin concentrations in cerebrospinal fluid of rabbits under normal and ischemic conditions.

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Prostaglandin concentrations in cerebrospinal fluid of rabbits under normal and ischemic conditions.

Clinical studies have demonstrated elevated levels of both arachidonic acid and prostaglandins in the cerebrospinal fluid of humans after ischemic stroke and subarachnoid hemorrhage. Such increases in free fatty acid, arachidonic acid, and prostaglandin concentrations suggest excessive production and accumulation of these substances in the ischemic brain. We used a rabbit model of ischemic infa...

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ژورنال

عنوان ژورنال: Stroke

سال: 1988

ISSN: 0039-2499,1524-4628

DOI: 10.1161/01.str.19.3.349