Prostaglandin concentrations in cerebrospinal fluid of rabbits under normal and ischemic conditions.
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Prostaglandin concentrations in cerebrospinal fluid of rabbits under normal and ischemic conditions.
Clinical studies have demonstrated elevated levels of both arachidonic acid and prostaglandins in the cerebrospinal fluid of humans after ischemic stroke and subarachnoid hemorrhage. Such increases in free fatty acid, arachidonic acid, and prostaglandin concentrations suggest excessive production and accumulation of these substances in the ischemic brain. We used a rabbit model of ischemic infa...
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Zinc concentrations in CSF were determined with flame atomic absorption spectrophotometry in patients assumed to have a normal CSF. No sex difference was found. There was a correlation between zinc, protein and albumin concentrations in CSF. In patients with increased protein levels in CSF or subarachnoid haemorrhage increased zinc concentrations were found.
متن کاملEffect of endothelin on production of cerebrospinal fluid in rabbits.
BACKGROUND AND PURPOSE Endothelin is a potent vasoconstrictor in several tissues, including the choroid plexus. The goal of this study was to determine whether endothelin affects the production of cerebrospinal fluid. METHODS Ventriculocisternal perfusion was used to measure the production of cerebrospinal fluid in anesthetized rabbits. Changes in production of cerebrospinal fluid were examin...
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ژورنال
عنوان ژورنال: Stroke
سال: 1988
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.19.3.349